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They were referred to a detoxification unit if they did not have an indication for hospitalization after the observation period.

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The effectiveness of the design comes partly from a paradox that is not seen in most placebo-controlled prospective trials: Usual care in the placebo group is supportive only; in the treatment group the study drug is presumed to be safe and reasonable enough to give to impaired patients with their informed consent still pending. Avoid using other medicines that make you sleepy emulsify prescription lorazepam as though.
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